LC-MS/MS Archives - AIT BioscienceAIT Bioscience


Tag Archives for LC-MS/MS

AIT Bioscience Announces New High-Resolution Mass Spectrometry Service Line

Synergistic Addition to Protein, Peptide, Antibody,   and ADC Offerings     At AIT Bioscience, we recently expanded our service offerings to include high-resolution mass spectrometry (HRMS).The Thermo Q-Exactive Plus® platform allows us to offer new capabilities in mass spectrometry including assays for conjugated peptides, fusion proteins, antibodies, and antibody drug conjugates (ADC’s). These HRMS … read the full article » »

Categories: High-Resolution Mass Spectrometry (HRMS), LC-MS/MS Methods, Ligand Binding Assays (LBA)

Other Tags: , , , , , , ,

Comments Off on AIT Bioscience Announces New High-Resolution Mass Spectrometry Service Line


AIT Bioscience Attends Land O’Lakes Bioanalytical Conference

Shelby Anderson, Chief Scientific Officer, Presents Poster     From July 9th to12th, AIT Bioscience’s Chief Scientific Officer, Shelby Anderson, Ph.D., attended the 2018 Land O’ Lakes Bioanalytical Conference in Madison, Wisconsin. The three-day conference encourages an open exchange of scientific and methodological applications for bioanalysis.   During the conference, AIT Bioscience presented a poster … read the full article » »

Categories: Events, News, Special Topics

Other Tags: , , , , , , , ,

Comments Off on AIT Bioscience Attends Land O’Lakes Bioanalytical Conference


AIT Bioscience Acquires New Instrumentation

New Mass Spectrometer Expands Lab Capacity     AIT Bioscience recently invested in a new Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer. This new instrument will allow AIT Bioscience to enhance its discovery protein mass spec capabilities and create additional capacity for protein and peptide work. This equipment will also improve method sensitivity and provide added … read the full article » »

Categories: LC-MS/MS Methods, Ligand Binding Assays (LBA)

Other Tags: , , , ,

Comments Off on AIT Bioscience Acquires New Instrumentation


AIT Bioscience Presents at 12th Annual Workshop on Recent Issues in Bioanalysis

  From April 9 – April 13, 2018, Philadelphia, PA was the host city for the 12th Annual Workshop on Recent Issues in Bioanalysis (WRIB). This conference brings together representatives of small and large pharmaceutical companies, regulators from around the world and toxicology and bioanalytical providers. AIT Bioscience was fortunate to have representation from three … read the full article » »

Categories: Biomarkers, LC-MS/MS Methods, Ligand Binding Assays (LBA)

Other Tags: , ,

Comments Off on AIT Bioscience Presents at 12th Annual Workshop on Recent Issues in Bioanalysis


AIT Bioscience’s Solution to a Tricky Peptide

AIT Bioscience’s Solution to a Tricky Peptide Triptorelin LC-MS/MS Case Study   Triptorelin is used for the treatment of estrogen-dependent conditions, certain cancers, and assisted reproduction in livestock. In the treatment of advanced prostate cancer, it is a gonadotropin-releasing hormone agonist marketed by Watson Pharmaceuticals as Trelstar and typically administered as an intramuscular injection.   … read the full article » »

Categories: LC-MS/MS Methods

Other Tags: , ,

Comments Off on AIT Bioscience’s Solution to a Tricky Peptide


Bioanalytical Considerations for your Dermal Pharmaceutical Programs

Bioanalytical Considerations for your Dermal Pharmaceutical Programs Does your drug require sustained release or suffer from first pass metabolism losses?   Have you considered transdermal delivery via cream gel or patch?   How does bioanalysis differ for oral or dermal delivery?   The dermis is the largest organ of the human body and provides a … read the full article » »

Categories: LC-MS/MS Methods, Screening Assay, Special Topics

Other Tags: , , , ,

Comments Off on Bioanalytical Considerations for your Dermal Pharmaceutical Programs


Bioanalytical Method Development Strategy for Proteins

By: Michael Schneider   A bioanalytical method development strategy is presented for quantitative protein analysis by LC-MS/MS when no capture antibody is available for bioanalytical sample clean-up or enrichment. A robust quantitative method for protein therapeutics can be quickly developed and performed in less than a day by using the Perfinity Workstation for on-line sample … read the full article » »

Categories: LC-MS/MS Methods, Proteins and LC-MS/MS

Other Tags: , , , ,

Comments Off on Bioanalytical Method Development Strategy for Proteins