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AIT Bioscience Among Inc.’s 5000 Fastest Growing Private Companies

AIT Bioscience Named to Inc. Magazine’s 36th Annual List of America’s Fastest-Growing Private Companies—the Inc. 5000   For the 2nd Time, AIT Bioscience appears on the Inc. 5000 list, Ranking No. 2366 with Three-Year Sales Growth of 153.16%   Indianapolis, IN August 16, 2017 – Inc. magazine today ranked AIT Bioscience NO. 2366 on its … read the full article » »

Categories: Biomarkers, LC-MS/MS Methods, Ligand Binding Assays (LBA), News, Screening Assay

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Ready to Roll; an Efficient Screening Level Assay Process

Back in January we wrote about fit-for-purpose bioanalytical assay support and announced a new small molecule LC-MS/MS screening level assay service at AITB.  Well, we’ve put this process through its paces and have shown our ability to consistently get variability down below 35% and in many cases down below 20%.  For a go-no/go decision point … read the full article » »

Categories: News, Screening Assay, Uncategorized

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American Society of Mass Spectrometry in Indy

From June 4-8, the city of Indianapolis got the privilege of playing host to nearly 6500 scientists from around the world who gathered to discuss all aspects of using mass spectrometry in a wide variety of applications. Several of our scientists were able to attend talks, workshops, and short-courses on LC-MS for antibody drug conjugates, proteins, … read the full article » »

Categories: LC-MS/MS Methods, Ligand Binding Assays (LBA), News

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The People at AIT Bioscience have been Busy

Jasmine Roach passes Registered Quality Assurance Professionals Exam. In late April, Jasmine Roach, Quality Assurance Specialist, sat for the Registered Quality Assurance Professionals Exam for GLP. Jasmine passed this exam on her first try. This certification is highly regarded by quality professionals internationally. As of December 2016, only 620 people worldwide had successfully passed this exam. Jasmine … read the full article » »

Categories: News, Quality Assurance and Electronic Laboratory Notebooks, Special Topics

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AIT Bioscience Attends Bio+Tech17 and AAPS NBC Conferences

AIT Biosciences recently attended the Bio+Tech17 Conference in Bethesda, Maryland from April 27-28, 2017 and the AAPS NBC Conference in San Diego, California from May 1-3, 2017. Below are summaries of both conferences:     Bio+Tech17 Conference   The conference is run by the MD Tech Council and seeks to bring together innovators from across the … read the full article » »

Categories: LC-MS/MS Methods, Ligand Binding Assays (LBA), Proteins and LC-MS/MS, Special Topics, Uncategorized

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Treating a Troublesome Biomarker Assay

By: Andrew Mayer   At AIT Bioscience we have established a sandwich ELISA optimized for the quantitative determination of human macrophage-colony stimulating factor (M-CSF), also known as colony stimulating factor-1 (CSF-1), from bulk critical reagents.  Up-regulation of M-CSF has been shown with viral infections, as well as many inflammatory diseases.  M-CSF can have a dual … read the full article » »

Categories: Biomarkers, ELISA, Immunoassay

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Tailoring ELN Workflows

  By: Ron Shoup   Setting up an Electronic Lab Notebook requires time, money, and most importantly, knowledge of the workflows that are performed in your laboratory.   As lab scientists, we sometimes overlook the inherent flexibility and numerous options that paper-based forms offer, whether for informal research or regulated analysis.  For example, graduate students can … read the full article » »

Categories: Electronic Lab Notebooks (ELN)

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Bioanalytical Method Development Strategy for Proteins

By: Michael Schneider   A bioanalytical method development strategy is presented for quantitative protein analysis by LC-MS/MS when no capture antibody is available for bioanalytical sample clean-up or enrichment. A robust quantitative method for protein therapeutics can be quickly developed and performed in less than a day by using the Perfinity Workstation for on-line sample … read the full article » »

Categories: LC-MS/MS Methods, Proteins and LC-MS/MS

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Strategy for Designing Electronic Lab Notebook Workflows Both Flexible Enough for R&D and Comprehensive Enough for Regulated Work

By: Brian D. Beato*; April L. Pisek; Jessica M. White   Electronic laboratory notebook (ELN) workflows are typically designed for either research or regulated use. Documentation requirements for regulated sample analysis are unnecessarily comprehensive and rigid for free-form research. Creating and validating separate templates targeted for different uses is inefficient. Presented here is a widely applicable, strategy for … read the full article » »

Categories: Electronic Lab Notebooks (ELN)

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Efficient Strategy for Generating Method-Specific Workflows in an Electronic Lab Notebook

By: Brian D. Beato; Jessica M. White; and April L. Pisek   One common concern among scientists regarding implementing an electronic laboratory notebook (ELN) is that method-specific workflows (or templates) may either lack sufficient detail to be useful, or require repeated validation exercises for each new method. However, with the widely applicable strategy for designing ELN workflows outlined … read the full article » »

Categories: Electronic Lab Notebooks (ELN)

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