List of Assays

Finding a Bioanalytical PK assay that meets 100% of your study’s needs can be a challenge. Often, tweaks to a variety of parameters such as the LLOQ, dynamic range, anticoagulant and species are necessary, requiring lab time before subject enrollment. AITB validates assays efficiently and accurately by employing its vast experience with small molecules, large biotherapeutics and a variety of methodologies ranging from mass spectrometry to ligand binding.

 

Integrating assay development experience, industry leading quality systems, and efficient lab operations, we can deliver QA weeks ahead of industry standards. We work collaboratively with clinical and Tox sites to ensure studies flow smoothly.

 

Can’t find what you’re looking for in this list? Check out a list of assays under development.

 

Have a specific question?  Call or email Bo Kowalczyk, VP of Business Development, 1-708-698-1090, Bo@aitbioscience.com

 

Analyte(s) BAM Range BAM Validation Level Anticoagulant Species Matrix
Ritonavir 10.0-10,000 Full Regulatory K2 EDTA Human Plasma
Ondansetron 0.250 – 250 Full Regulatory K2 EDTA Human Plasma
Melatonin 1.00-1,000 Full Regulatory NA Human Saliva
Simvastatin and Simvastatin Hydroxy Acid 50.0-50,000 Full Regulatory K2 EDTA Human Plasma
 Fentanyl 5.00-5,000 Full Regulatory K2 EDTA Human Plasma
Morphine, Oxycodone and Morphine-6-Glucuronide 0.200-50.0, 0.400-100 Full Regulatory K2 EDTA Human Plasma
Ketoprofen 1.00-1,000 Full Regulatory K2 EDTA Human Acidified Plasma (30mg-mL Citric Acid)
 (R)-Methadone and (S)-Methadone 1.00-1,000 Full Regulatory K2 EDTA Human Plasma
 Nordiazepam 0.500-500 Full Regulatory K2 EDTA Human Plasma
Clorazepate 0.500-500 Full Regulatory K2 EDTA Human Plasma
Diclofenac 0.100-1,000 Full Regulatory K2 EDTA Human Plasma
Atorvastatin, 2-Hydroxyatorvastatin, and 4-Hydroxyatorvastatin 50.0-50,000, 20.0-20,000 Full Regulatory K2 EDTA Human Plasma
 Hydrocodone, Hydromorphone,  Norhydrocodone and  Acetaminophen 0.100-100, 50.0-50,000 Full Regulatory K2 EDTA Human Plasma
Rosuvastatin 0.100-100 Full Regulatory K2 EDTA Human Plasma
Pravastatin 0.100-100 Full Regulatory K2 EDTA Human Plasma
 (R)-Amphetamine and (S)-Amphetamine 0.200-200 Full Regulatory K2 EDTA Human Plasma
 Ropivacaine 1.00-1,000 Full Regulatory K2 EDTA Human Plasma Ultrafiltrate
Ropivacaine 1.00-1,000 Full Regulatory K2 EDTA Human Plasma
 Fentanyl 5.00-5,000 Full Regulatory K2 EDTA Human Plasma
Ethinyl Estradiol and Norethindrone 7.50-7,500, 100-100,000 Full Regulatory K2 EDTA Human Plasma
Caffeine metabolies 1MX and AFMU 100-100,000 Full Regulatory NA Human Urine, Charcoal Stripped (2x)
 Isradipine 0.100- 100 Full Regulatory K2 EDTA Human Plasma
 Metformin 5.00-5,000 Full Regulatory K2 EDTA Human Plasma
Anti-Insulin Antibodies 100 – 1,000 Full Regulatory NA Human Serum