Publications and Presentations -AIT Bioscience

Publications and Presentations

Access Expert Contract Research Produced By Our Scientists

AIT Bioscience’s team is comprised of industry veterans with extensive experience in the scientific and regulatory aspects of contract research. Learn more about our team’s collective experience by reviewing their professional works below. Research includes presentations, conference posters, publications, and seminar information.

Journal Papers

PK and Immunogenicity in Biosimilar Research

 

Robust Assay Designs

In Contract Pharma’s October issue, AITB tackles this topic to highlight where some unexpected challenges and expenses can arise and how these can be overcome.

By Franklin Spriggs, Stephanie Mowery and Bo Kowalcyk, AIT Bioscience

 

Fit-for-Purpose Assay Development in Bioanalysis

The success of bioanalytical studies relies on the selection of the most suitable
analytical method but the timeline of method development and types of analyses
involved vary greatly.

By Frank Spriggs and Ashley Brant, AIT Bioscience

 

Is it Time to Rethink Your ELN?
Existing technology is revolutionizing bioanalytical labs that are now deploying it to their fullest potential.

By Bo Kowalcyzk, Vice President of Business Development, AIT Bioscience

View as PDF

 

Partnering with CROs to Develop High-Quality ADCs
Key Bioanalytical Strategies
ADCs are a breakthrough cancer treatment that can deliver cytotoxins directly to cancer cells without the sweeping collateral damage of traditional chemotherapy.

By Franklin Spriggs, Stephanie Mowery, and Bo Kowalcyk, AIT Biosciences

View as PDF

 

A Case for One Assay Analysis of PK and Immunogenicity in Biosimilar Research
Moving forward clinical studies will have to include a comparative assessment of pharmacokinetics and immunogenicity to the original reference biologic drug

By Stephanie Mowery, Sherri Rinker, Franklin Spriggs and Bo Kowalcyk , AIT Bioscience

 

Going Paperless: Implementing an Electronic Laboratory Notebook in a Bioanalytical Laboratory

By Brian Beato, Ph.D., Laurel Branstrator, Barbara Carel, Brian Engel, Timothy Grever, April Pisek,
Michael Pugh, Michael Schneider, Ronald Shoup, Ph.D., and Jessica White
Published in the July 2011 issue of the industry journal Bioanalysis

Poster Presentations

Development of LC-MS/MS Method in Plasma for Cocaine and metabolites Benzoylecgonine and Ecgonine Methyl Ester

By: Brad King, Ashley Brant, Jennifer Vance, Julie Straub, Ronald Shoup

Presented at the 65th ASMS Conference on Mass Spectrometry and Allied Topics

June 4-8, 2017

 

Development of LC-MS/MS Methods in Plasma for SPR741, a Cyclic Nonapeptide Which Potentiates Antibiotic Activity Against Gram-negative Pathogens

By: Brad King, Abram Brubaker, Robert Lappin, Jennifer Vance, Ronald Shoup, Luke Utley

Presented at the 65th ASMS Conference on Mass Spectrometry and Allied Topics

June 4-8, 2017

 

Electronic Laboratory Notebook as a tool to Facilitate Scientific Data Analysis and Review in Regulated and Non-Regulated Bioanalysis

By: Jessica White, April Pisek, Jennifer Vance, Ashley Brant

Presented at the 11th annual WRIB in Los Angelos/Universal City, CA

April 3-7, 2017

 

Chiral Derivatization of D-and L-Eflornithine for Enantiomer Identification from a Racemateand Chromatographic Separation Poster ELN data handling

By: Abram Brubaker, Neal Simmons, Ashley Brant, Ronald Shoup

Presented at the 11th annual WRIB in Los Angelos/Universal City, CA

April 3-7, 2017

 

ELISA Assay Buffer Additives to Solve Matrix Interferences in a Biomarker Assay

By: Andrew P. Mayer, Michael L. Schneider, Ronald R. Bowsher

Presented at the AAPS National Biotech Conference in San Diego, CA

May 20-22, 2013

 

Going Paperless: Auditing in an Electronic Bioanalytical Laboratory

By: Jasmine Roach; Laurel Branstrator; Abby Bousum

Presented at the 29th SQA Annual Meeting & Quality College – Indianapolis, Indiana, USA

April 29 – May 3, 2013

 

Tailoring ELN Workflows to the Variations in Regulatory Requirements for Contracted Studies

By:  Ron Shoup, April Pisek, Jessica White, Brian Beato

Presented at the Applied Pharmaceutical Software meeting in Langhorne, PA

June 13, 2012

 

Bioanalytical LC-MSMS Method Development for Proteins Without Sample Clean-up or Enrichment

By: Michael Schneider and Kevin Meyer

Presented at AAPS in San Diego, CA

May 21-23, 2012

 

A Paper-free Fully Regulated Bioanalytical Assay Validation of Fentanyl in Human Plasma

By Brian Engel, Michael Pugh, Barbara Carel, and Ron Shoup, Ph.D.
Presented at AAPS in Washington, D.C.
October 27, 2011

Efficient Strategy for Generating Method-Specific Workflows in an Electronic Lab Notebook

By Brian Beato, Ph.D., Jessica White, and April Pisek
Presented at AAPS in Washington, D.C.
October 27, 2011

Strategy for Designing Electronic Lab Notebook Workflows Both Flexible Enough for RD
By Brian Beato, Ph.D., April Pisek, and Jessica White
Presented at AAPS in Washington, D.C.
October 27, 2011

Using Electronic Lab Notebook Functionality for Validating Electronic Lab Notebook Workflows

By Brian Beato, Ph.D., Tim Grever, and Laurel Branstrator
Presented at AAPS in Washington, D.C.
October 24, 2011

Qualification of a Robotic Liquid Handler to Prepare Bioanalytical Runs
By Ron Shoup, Ph.D., and Michael Pugh
Presented at AAPS in Washington, D.C.
October 24, 2011

Auditing a Regulated Study Utiliziing an Electronic Laboratory Notebook (ELN)

By Abby Bousum and Laurel Branstrator
Presented at the Indiana/Ohio AAPS Discussion Group Symposium
August 9, 2011

Automated and Validated Bioanalytical LC MS MS Data Analysis
By April Pisek, Jessica White, and Michael Schneider
Presented at the American Society for Mass Spectrometry (ASMS) meeting in Denver, Colorado,
June 5-9, 2011

A Rapid LC-MS/MS Alternative to the Isotope Dilution GC-MS NIST Reference Measurement Procedure for Determining Glucose in Human Plasma
By Brian Beato, Ph.D., Michael Pugh, and David Hulbert
Presented at the American Society for Mass Spectrometry (ASMS) meeting in Denver, Colorado,
June 5-9, 2011

Rapid, Automated, and Validated Evaluation of Carryover Acceptance and ImpactBy Brian Engel, Brian Beato, Ph.D., and Michael Pugh
Presented at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in New Orleans, November 14-18, 2010

A Superior Way to Measure Carryover
By Brian Beato, Ph.D. and Brian J. Engel
Presented at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in New Orleans, November 14-18, 2010

Automated Processes for Sample Accessioning and Data Scrubbing
By Barbara Montague, April Pisek, and Jessica White
Presented at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in New Orleans, November 14-18, 2010

Streamlining Bioanalytical Processes with QC in Real Time
By J. Rajarao, Brian Beato, Ph.D., S. Weiss, April Pisek, Laurel Branstrator, Tim Grever, and Ron Shoup, Ph.D.
Presented at Applied Pharmaceutical Analysis in Baltimore, MD
September 9, 2010

Podium Presentations

 

Reaping the Benefits: A Highly Configured ELN in a Bioanalytical Laboratory
By Abby Bousum
Presented at the 29th SQA Annual Meeting & Quality College – Indianapolis, Indiana, USA
April 30, 2013

 

Electronic Raw Data and the Use of Electronic Laboratory Notebooks
By Ron Shoup, Ph.D.
Presented at 7th WRIB Workshop in Long Beach, CA
April 9, 2013

 

Accelerating Data Review in a Paperless Laboratory with ELN
By Ron Shoup, Ph.D.
Presented at AAPS in Washington, D.C.
October 24, 2011

How To Implement a Validated Method
By Ron Shoup, Ph.D.
Presented at CPSA in Langhorne, PA
October 19, 2010

My Hamilton Can Beat Your Analyst
By Ron Shoup, Ph.D.
Presented at CPSA in Langhorne, PA
October 18, 2010

Implementation of an ELN in a CRO Environment

By Ron Shoup, Ph.D.
Presented at Applied Pharmaceutical Software in Langhorne, PA
July 28, 2010

A Systems Integration Approach for Fully Electronic Regulated Bioanalysis

By Brian Beato, Ph.D.
Presented at the 2010 ASMS Meeting
June 2010

Implementation of an ELN in a CRO Environment
By Ron Shoup, Ph.D.
Presented at the IDBS Users’ Group Meeting in Northbrook, IL
May 25, 2010