Biomarkers Archives - AIT BioscienceAIT Bioscience


Category Archives for Biomarkers

AIT Bioscience Among Inc.’s 5000 Fastest Growing Private Companies

AIT Bioscience Named to Inc. Magazine’s 36th Annual List of America’s Fastest-Growing Private Companies—the Inc. 5000   For the 2nd Time, AIT Bioscience appears on the Inc. 5000 list, Ranking No. 2366 with Three-Year Sales Growth of 153.16%   Indianapolis, IN August 16, 2017 – Inc. magazine today ranked AIT Bioscience NO. 2366 on its … read the full article » »

Other Categories: LC-MS/MS Methods, Ligand Binding Assays (LBA), News, Screening Assay

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Antibody Drug Conjugate Analysis: How Partnering with a Bioanalytical CRO Can Ease Preclinical ADC Programs

The potential of antibody drug conjugates (ADCs) to provide targeted therapies for cancers and other devastating diseases have made them popular candidates for drug development programs. However, as we discussed recently in Drug Discovery and Development, the failure of several ADCs during phase II and III trials due to limited efficacy proves more complete bioanalysis … read the full article » »

Other Categories: LC-MS/MS Methods, Ligand Binding Assays (LBA), Partnerships



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Critical Reagents Consideration for Ligand Binding Assays

Ligand binding assays (LBAs) are bioanalytical procedures commonly used to support biotherapeutic development. These assays are used for the characterization of pharmacokinetics, biomarkers, and/or immunogenicity.  LBAs, unlike classic LC-MS/MS, utilize the interactions of a biotherapeutic and proteins used as critical reagents to detect the analyte of interest.  Therefore, special considerations must be made in the … read the full article » »

Other Categories: ELISA, Immunoassay, Ligand Binding Assays (LBA)



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Treating a Troublesome Biomarker Assay

By: Andrew Mayer   At AIT Bioscience we have established a sandwich ELISA optimized for the quantitative determination of human macrophage-colony stimulating factor (M-CSF), also known as colony stimulating factor-1 (CSF-1), from bulk critical reagents.  Up-regulation of M-CSF has been shown with viral infections, as well as many inflammatory diseases.  M-CSF can have a dual … read the full article » »

Other Categories: ELISA, Immunoassay

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