Bo Kowalczyk, Author at AIT BioscienceAIT Bioscience


Author Archives: Bo Kowalczyk

AIT Bioscience Attends Bio+Tech17 and AAPS NBC Conferences

AIT Biosciences recently attended the Bio+Tech17 Conference in Bethesda, Maryland from April 27-28, 2017 and the AAPS NBC Conference in San Diego, California from May 1-3, 2017. Below are summaries of both conferences:     Bio+Tech17 Conference   The conference is run by the MD Tech Council and seeks to bring together innovators from across the … read the full article » »

Categories: LC-MS/MS Methods, Ligand Binding Assays (LBA), Proteins and LC-MS/MS, Special Topics, Uncategorized

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AIT Bioscience Recognized with Awards at Recent WRIB

  WRIB (Workshop for Recent Issues in Bioanalysis) is an annual gathering of bioanalytical scientists from across the pharmaceutical industry spectrum. Attendees include big pharma and biopharmas, biotechs, CROs and multiple regulatory agencies working on both small and large molecule bioanalysis.   Ashley Brant and Dr. Neal Simmons represented AIT Bioscience (AITB) discussing LC-MS/MS assays, … read the full article » »

Categories: Ligand Binding Assays (LBA), Proteins and LC-MS/MS, Special Topics

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AIT Bioscience Strengthens its Team with Recent Hires

AIT Bioscience (AITB) continues to expand its team to add breadth and depth to our areas of expertise. We are excited to introduce three new employees, who have already been great assets to AITB.     John Pirro     John Pirro recently joined AITB’s business development team. John earned a B.S. in Cell Biology … read the full article » »

Categories: Ligand Binding Assays (LBA)



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Involved in Ocular Therapeutics? Thoughts on a successful PK program

As our population ages there comes an increased demand for therapies to treat age related ocular diseases such as Age-related Macular Degeneration (AMD), glaucoma, diabetic retinopathy and dry-eye.  In fact, the global market for ocular drugs is expected to reach $21.6 billion by 2018 according to a Transparency Market Research article.   Successful bioanalysis in … read the full article » »

Categories: Special Topics

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AIT Bioscience Featured in Contract Pharma

As sponsors transition their programs from preclinical animal Tox studies to human clinical trials, sponsors turn to AIT Bioscience (AITB) to help understand the potential issues that may arise with their bioanalytical PK assays. In Contract Pharma’s October issue, AITB tackles this topic to highlight where some unexpected challenges and expenses can arise (Robust Assay … read the full article » »

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AIT Bioscience Expands Our Breadth and Depth with New Hires

AIT Bioscience is expanding! As part of this growth we’ve added two new members to our team:     Qian Li began working for AITB as a Sr. Scientist II in our LC-MS/MS assay development and validation group. She is originally from China and received a master’s degree in organic chemistry there. She then received … read the full article » »

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Antibody Drug Conjugate Analysis: How Partnering with a Bioanalytical CRO Can Ease Preclinical ADC Programs

By: Frank Spriggs, Ligand Binding Assay Group Leader, and Ashley Brant, Program Manager   The potential of antibody drug conjugates (ADCs) to provide targeted therapies for cancers and other devastating diseases have made them popular candidates for drug development programs. However, as we discussed recently in Drug Discovery and Development, the failure of several ADCs … read the full article » »

Categories: Biomarkers, LC-MS/MS Methods, Ligand Binding Assays (LBA), Partnerships



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Continuing to Expand our Capacity at AIT Bioscience

2016 is turning into a great year for AIT Bioscience (AITB) and our sponsors. Funding in the biotech market is up sharply over previous years and sponsors are moving programs forward at a rapid pace. From early preclinical non-GLP through clinical phase of development, our clients are pushing for more capacity to shorten program lead-times. … read the full article » »

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Therapeutic Peptides – Toeing the Line of Small and Large Molecule Bioanalysis

By: Bo Kowalczyk, Vice President of Business Development The pharmaceutical industry is so abuzz with the potential for biologic therapeutics that we often forget about peptide therapy. Despite boasting desirable qualities – low toxicity, high specificity, and high potency – the adoption of peptides into treatments faces many hurdles (Table 1). Design strategies that improve … read the full article » »

Categories: LC-MS/MS Methods, Ligand Binding Assays (LBA)



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What Level of Bioanalytical Method Validation is Right for My Early Stage Drug Development Study?

By: Franklin Spriggs, Ligand Binding Assay Group Leader; Ashley Brant, Program Manager During late phase drug discovery, everyone follows well established FDA bioanalytical method validation guidelines. However, opinions vary widely about what validation is necessary for early- to mid-phase studies. We are often asked by our clients: “How robust do I need this assay to … read the full article » »

Categories: LC-MS/MS Methods, Ligand Binding Assays (LBA), Partnerships



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